Tuberculosis Vaccines, Gebunden

Blurb

PART I: Introduction to tuberculosis.- 1. Introduction to tuberculosis and mycobacteriology.- PART II: Historical perspectives on BCG and tuberculosis vaccine candidates.- 2. 100 years of BCG against tuberculosis and other diseases.- 3. TB or not TB - The parallel lives of BCG.- 4. Induction of trained immunity and non-specific protective effects against heterologous diseases by BCG vaccination.- PART III: Pre-clinical vaccines against tuberculosis.- 5. New vaccine strategies to improve, boost, or replace BCG.- 6. Pre-clinical landscape of TB vaccines: challenges and innovations.- 7. Pre-clinical studies and animal models.- 8. Pre-clinical tuberculosis vaccine development: understanding immune response to infection to inform next generation vaccine development.- PART IV: Vaccines against tuberculosis in clinical trials.- 9. Novel prophylactic TB vaccines in clinical trials.- 10. Live attenuated vaccines in clinical trials.- 11. New vaccine strategies based on viral vectors and mRNA.- 12. Systems immunology and omics data from developing countries are needed to inform vaccine development.- PART V: Public Health and Societal challenges for the development of TB vaccines.- 13. Public health strategies and prevention of tuberculosis.- 14. Technological advances applied to TB vaccine development: how can AI contribute to the development of new TB vaccines?.- 15. From cutting edge science to innovative finance: the road to TB vaccine implementation.